TFAM
Description
TFAM, short for Transcription Factor A, Mitochondria, is a nuclear-encoded protein that plays a vital role in regulating mitochondrial DNA (mtDNA) replication and transcription. This protein binds to the mtDNA control region, facilitating the assembly of the mitochondrial transcription and replication machinery. TFAM ensures the proper expression of mitochondrial genes, essential for cellular energy production and other critical functions.
Associated Diseases
Did you know?
TFAM‘s ability to regulate mtDNA copy number is crucial for maintaining cellular energy production. This is why mutations in TFAM can lead to a wide range of human diseases.
