MEG8
Megaesophagus (Meg8): A Comprehensive Guide
Description
Megaesophagus is a rare and serious condition characterized by the abnormal widening of the esophagus, the tube that transports food from the mouth to the stomach. This enlargement impairs the proper function of the esophagus, leading to difficulty swallowing and regurgitation of food and fluid.
The esophagus normally propels food and liquid downward through rhythmic muscular contractions called peristalsis. In individuals with megaesophagus, peristalsis is weakened or absent, resulting in the accumulation of food and fluid in the esophagus. Over time, this can lead to inflammation, infection, and other complications.
Associated Diseases
Megaesophagus can be a primary condition or secondary to an underlying disease. Conditions that may be associated with megaesophagus include:
- Autoimmune disorders (e.g., myasthenia gravis)
- Neurological disorders (e.g., stroke, multiple sclerosis)
- Respiratory disorders (e.g., pneumonia, aspiration)
- Congenital abnormalities
- Muscle disorders (e.g., muscular dystrophy)
- Medications (e.g., potassium supplements, certain antibiotics)
Did you Know ?
The exact prevalence of megaesophagus is unknown, but it is estimated to affect approximately 1 in 100,000 people worldwide. It is more common in older dogs and certain breeds, such as German Shepherds and Great Danes.
