IFNL3
Description
The IFNL3 gene, also known as IL28B, plays a crucial role in the immune response to viral infections, particularly hepatitis C virus (HCV). It encodes a type III interferon, a signaling molecule that activates antiviral pathways within cells. Variations in the IFNL3 gene have been linked to differences in HCV treatment response and susceptibility to other viral infections.
Associated Diseases
- Hepatitis C Virus (HCV) Infection
- Chronic Hepatitis B Virus (HBV) Infection
- HIV Infection
- Influenza
- Dengue Fever
- COVID-19
Did you know?
Genetic variations in the IFNL3 gene are one of the strongest predictors of response to pegylated interferon and ribavirin therapy for chronic HCV infection.
