The DPYD gene encodes an enzyme called dihydropyrimidine dehydrogenase (DPD). Reduced DPD activity affects the metabolism of certain chemotherapy drugs,

Associated Diseases

Fluoropyrimidine Metabolism, Dihydropyrimidine Dehydrogenase Deficiency

Did you Know

  • The DPYD gene provides instructions for creating the DPD enzyme.
  • DPD is involved in the breakdown of molecules called uracil and thymine when they are no longer needed.
  • Uracil and thymine are pyrimidines, which are essential components of nucleotides—building blocks of DNA, RNA, and cellular energy sources like ATP and GTP.

Disclaimer: The information provided here is not exhaustive by any means. Always consult your doctor or other qualified healthcare provider with any questions you may have regarding a medical condition, procedure, or treatment, whether it is a prescription medication, over-the-counter drug, vitamin, supplement, or herbal alternative.