CYP3A5

CYP3A enzymes are the most abundantly expressed cytochrome P450 enzymes in liver and are responsible for the metabolism of over 50% of all clinically used drugs 

Associated Diseases

Drug Metabolism, Tacrolimus Response

Did you Know

• CYP3A5 is involved in drug metabolism and the synthesis of cholesterol, steroids, and other lipids.
• It catalyzes reactions that help process drugs such as nifedipine, cyclosporine, and steroid hormones like testosterone, progesterone, and androstenedione.