LY96
LY96: An Overview
Description:
LY96 is a protein that plays a crucial role in the regulation of the immune system. It belongs to the Ly6 family of proteins, which are known for their involvement in immune cell recognition and adhesion. LY96 is specifically expressed on the surface of certain immune cells, including T cells, B cells, and natural killer (NK) cells.
Associated Diseases:
LY96 has been implicated in the development and progression of several autoimmune disorders, including:
- Multiple sclerosis (MS): LY96 is believed to contribute to the inflammatory response in MS, leading to damage to the central nervous system.
- Rheumatoid arthritis (RA): LY96 may regulate the activity of immune cells involved in joint inflammation in RA.
- Systemic lupus erythematosus (SLE): LY96 is thought to be involved in the production of autoantibodies that attack the body's own tissues in SLE.
Did you Know ?
Studies have shown that individuals with certain genetic variations in the LY96 gene have an increased risk of developing MS. One such variation, the rs11266958 allele, is associated with a nearly twofold increase in the risk of MS.
