LSP1
Description
The LSP1 (lymphocyte specific protein 1) is a protein-coding gene located on chromosome 11.
Lymphocyte-specific protein 1 is a protein that in humans is encoded by the LSP1 gene. This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms.
May play a role in mediating neutrophil activation and chemotaxis.
LSP1 is also known as WP34, pp52.
