LRRTM2
Description
The LRRTM2 (leucine rich repeat transmembrane neuronal 2) is a protein-coding gene located on chromosome 5.
LRRTM2 plays a crucial role in the formation and upkeep of excitatory synapses in the nervous system of vertebrates. It controls the amount of AMPA receptors on the cell surface and directs the development of sites where glutamate, an important neurotransmitter, is released. LRRTM2 acts as a signaling molecule for the presynaptic receptors NRXN1-A and NRXN1-B, influencing communication between neurons.
LRRTM2 is also known as -.
Associated Diseases
- thyroid gland adenocarcinoma
- Senior-Boichis syndrome
- hepatorenocardiac degenerative fibrosis
- renal-hepatic-pancreatic dysplasia 1
- immunodeficiency 75
- renal-hepatic-pancreatic dysplasia
- nephronophthisis 16
- nephronophthisis
- neutropenia, severe congenital, 9, autosomal dominant
- sickle cell anemia
- hemoglobin H disease
