LRRC4B
Description
The LRRC4B (leucine rich repeat containing 4B) is a protein-coding gene located on chromosome 19.
LRRC4B is a synaptic adhesion protein that plays a role in regulating the formation of excitatory synapses. Its interaction with PTPRF, another protein, forms a bidirectional connection that influences the development of these synapses.
LRRC4B is also known as HSM, LRIG4, NGL-3.
Associated Diseases
- developmental and epileptic encephalopathy, 43
- Lennox-Gastaut syndrome
- developmental and epileptic encephalopathy 104
- late infantile neuronal ceroid lipofuscinosis
- cortical dysplasia-focal epilepsy syndrome
- obesity due to leptin receptor gene deficiency
- developmental and epileptic encephalopathy, 9
- neuronal ceroid lipofuscinosis 8 northern epilepsy variant
- developmental and epileptic encephalopathy, 4
- growth delay due to insulin-like growth factor type 1 deficiency
- cancer
- bipolar disorder
- encephalitis
