SIRT 1

SIRT-1 is a member of the sirtuin family of proteins involved in cellular stress response, metabolism, and longevity.

Function

SIRT-1 regulates gene expression through deacetylation. It impacts various cellular processes, including DNA repair, inflammation, and energy metabolism.

Significance

    • Aging and Longevity: SIRT-1 is associated with lifespan extension in model organisms. Caloric restriction activates SIRT-1 and promotes healthspan.

    • Metabolic Health: SIRT-1 influences glucose homeostasis, insulin sensitivity, and mitochondrial function.

Associated Diseases

Cancer and Neurodegeneration: Dysregulation of SIRT-1 is implicated in cancer, neurodegenerative diseases, and cardiovascular health.


Login to View More

Related Products

WES Whole Exome Sequencing

Clinical Exome Sequencing

Disclaimer: The information provided here is not exhaustive by any means. Always consult your doctor or other qualified healthcare provider with any questions you may have regarding a medical condition, procedure, or treatment, whether it is a prescription medication, over-the-counter drug, vitamin, supplement, or herbal alternative.