LOC606724
Description
The LOC606724 (-) is a pseudo gene located on chromosome 16.
This gene encodes a protein that is a component of the oligosaccharyltransferase (OST) complex. The OST complex is responsible for the transfer of N-glycans from dolichol-linked oligosaccharides to asparagine residues in nascent polypeptide chains. N-glycosylation is a crucial post-translational modification that is essential for proper protein folding, stability, and function. Mutations in this gene have been associated with congenital disorders of glycosylation (CDGs), a group of genetic disorders that affect the biosynthesis of N-glycans.
The protein encoded by this gene is a component of the oligosaccharyltransferase (OST) complex, which catalyzes the transfer of N-glycans from dolichol-linked oligosaccharides to asparagine residues in nascent polypeptide chains. The OST complex is essential for protein folding and stability, and defects in this complex can lead to a variety of diseases, including congenital disorders of glycosylation (CDGs).
LOC606724 is also known as -.
