LOC554223
Loc554223: An Emerging Molecular Target for Cancer Therapy
Description
Loc554223, also known as augmenter of liver regeneration (ALR), is a recently discovered protein that has emerged as a promising therapeutic target for cancer. It plays a crucial role in cell cycle regulation, DNA repair, and apoptosis, and its dysregulation is associated with various types of cancer.
Loc554223 is highly expressed in many cancer cells, including those in breast, lung, liver, and colorectal cancers. Its overexpression contributes to cancer development and progression by promoting cell proliferation, inhibiting apoptosis, and facilitating DNA repair. Additionally, Loc554223 is involved in tumor angiogenesis, invasion, and metastasis.
Associated Diseases
The dysregulation of Loc554223 has been linked to several types of cancer, including:
- Breast cancer: Loc554223 overexpression is associated with increased tumor size, poor prognosis, and resistance to chemotherapy.
- Lung cancer: High levels of Loc554223 have been linked to non-small cell lung cancer (NSCLC) progression and reduced survival rates.
- Liver cancer: Loc554223 overexpression promotes hepatocellular carcinoma (HCC) growth, invasiveness, and resistance to therapy.
- Colorectal cancer: Dysregulated Loc554223 expression contributes to colorectal cancer development and metastasis.
Did you Know ?
Studies have shown that Loc554223 overexpression is observed in up to 80% of breast cancer patients, highlighting its potential significance as a therapeutic target.
