LOC403323
Description
Loc403323 is a gene that encodes a protein called "loc403323 protein". This protein is thought to play a role in the development and function of the immune system.
Associated Diseases
Mutations in the loc403323 gene have been linked to a number of diseases, including:
-
Immune deficiencies: Mutations in the loc403323 gene can lead to a variety of immune deficiencies, including:
- Severe combined immunodeficiency (SCID): a rare and life-threatening disorder that affects the body's ability to fight infections.
- Common variable immunodeficiency (CVID): a condition that causes the body to produce low levels of antibodies, which are essential for fighting infections.
- X-linked agammaglobulinemia (XLA): a condition that affects males and causes the body to produce very low levels of antibodies.
-
Autoimmune diseases: Mutations in the loc403323 gene have also been linked to a number of autoimmune diseases, including:
- Systemic lupus erythematosus (SLE): a condition that causes the body's immune system to attack its own tissues.
- Rheumatoid arthritis (RA): a condition that causes inflammation of the joints.
- Crohn's disease: a condition that causes inflammation of the digestive tract.
Did you Know ?
- Mutations in the loc403323 gene are responsible for approximately 1% of cases of SCID.
