LOC391003
loc391003
Description:
LOC391003 is a long non-coding RNA (lncRNA) molecule located on chromosome 3q26.1. LncRNAs are regulatory RNA molecules that play various roles in cellular processes, including gene expression, cell differentiation, and disease development.
LOC391003 is expressed in various tissues, including the liver, kidney, and heart. Its exact function is still being studied, but it has been implicated in the regulation of cell proliferation, apoptosis, and migration.
Associated Diseases:
Dysregulation of LOC391003 expression has been linked to several diseases, including:
- Hepatocellular carcinoma (HCC): LOC391003 is upregulated in HCC and promotes tumor growth and metastasis.
- Kidney fibrosis: LOC391003 contributes to kidney fibrosis by regulating the expression of genes involved in extracellular matrix synthesis.
- Cardiovascular diseases: LOC391003 dysregulation is associated with heart failure and coronary artery disease.
Did you Know ?
In a study of HCC patients, high levels of LOC391003 were associated with a 30% higher risk of tumor recurrence and a 40% increased risk of mortality.
