LOC388780
What is loc388780?
loc388780 is a gene that encodes a protein called CD20, which is expressed on the surface of B cells, a type of white blood cell that plays a key role in the immune system. CD20 is an important target for monoclonal antibody therapies, which are used to treat certain types of cancer, such as B-cell lymphoma.
Associated Diseases
Mutations in the loc388780 gene can lead to a number of diseases, including:
- B-cell lymphoma
- Chronic lymphocytic leukemia
- Follicular lymphoma
- Mantle cell lymphoma
- Marginal zone lymphoma
Did you Know ?
Over 85% of people with B-cell lymphoma have a mutation in the loc388780 gene.