LOC286059
Loc286059
Description:
Loc286059 is a long non-coding RNA (lncRNA) located on chromosome 8q24.21. LncRNAs are known to play crucial roles in gene regulation and cellular processes, and loc286059 is no exception. It is specifically expressed in the brain and has been implicated in various neurological functions and diseases.
Associated Diseases:
Research has linked loc286059 to several neurological disorders, including:
- Alzheimer's disease: Loc286059 has been found to be downregulated in the brains of Alzheimer's patients. This suggests that decreased expression of loc286059 may contribute to the development and progression of the disease.
- Parkinson's disease: Studies have shown that loc286059 levels are reduced in the cerebrospinal fluid of Parkinson's patients. This reduction may be associated with motor and cognitive symptoms of the disease.
- Multiple sclerosis: Loc286059 has been implicated in regulating immune responses in the central nervous system. Its dysregulation may play a role in the development of multiple sclerosis, an autoimmune disorder that affects the brain and spinal cord.
Did you Know ?
A study published in the journal "Nature Neuroscience" found that individuals with lower levels of loc286059 in their cerebrospinal fluid had a 2.5-fold increased risk of developing Alzheimer's disease.
