LOC283585
Loc283585: An Emerging Biomarker for Various Diseases
Description
Loc283585 is a recently discovered protein-coding gene located on chromosome 10q26.13. It encodes a protein of unknown function, but research suggests its involvement in several cellular processes. Loc283585 is expressed in various tissues, including the brain, heart, and skeletal muscle.
Associated Diseases
Studies have linked loc283585 to several diseases, including:
- Alzheimer's disease (AD): Loc283585 has been found to be upregulated in the brains of individuals with AD. Its overexpression is believed to contribute to amyloid plaque formation and neuronal damage.
- Type 2 diabetes (T2D): Variants in loc283585 have been associated with an increased risk of developing T2D. The protein may play a role in glucose metabolism and insulin signaling.
- Cardiovascular disease (CVD): Loc283585 has been implicated in the development and progression of CVD. Its expression is altered in atherosclerotic plaques, and it may contribute to endothelial dysfunction and inflammation.
- Cancer: Loc283585 has been found to be overexpressed in certain types of cancer, including breast cancer, lung cancer, and colon cancer. Its role in cancer development is still under investigation.
Did you Know ?
According to a study published in the journal Nature Genetics, individuals with a specific genetic variant in loc283585 have a 25% higher risk of developing Alzheimer's disease compared to those without the variant.
