LOC150776
Loc150776: An Emerging Biomarker for a Spectrum of Diseases
Description:
Loc150776 is a long non-coding RNA (lncRNA), a type of RNA molecule that does not code for proteins. It is predominantly found in the cytoplasm and nucleus of cells and is involved in various cellular processes, including gene regulation and cell growth.
Associated Diseases:
Research has implicated loc150776 in the development and progression of several diseases, including:
- Cancer: Loc150776 overexpression has been linked to tumor growth, invasion, and metastasis in various cancers, including breast, lung, and liver cancer.
- Cardiovascular disease: Reduced loc150776 expression has been associated with increased risk of coronary artery disease and heart failure.
- Neurodegenerative diseases: Alterations in loc150776 levels have been observed in patients with Alzheimer's and Parkinson's disease, suggesting its involvement in neuronal dysfunction and cognitive decline.
- Immune disorders: Loc150776 dysregulation has been implicated in the development of autoimmune diseases, such as systemic lupus erythematosus and rheumatoid arthritis.
Did you Know ?
A study published in the journal "Cancer Research" found that patients with high loc150776 expression in breast tumors had a significantly shorter overall survival compared to those with low expression. This highlights the potential prognostic value of loc150776 in cancer.
