LOC105419998
Title: Loc105419998: A Gene Linked to Cardiomyopathy and Cancer
Introduction: Loc105419998 is a gene located on chromosome 22 in humans. This gene has been identified as a potential contributor to the development of cardiomyopathy, a condition that weakens the heart muscle, and certain types of cancer.
Description: The loc105419998 gene encodes a protein called uncharacterized protein C14orf166. The exact function of this protein is not fully understood, but research suggests that it plays a role in regulating cell growth and division.
Associated Diseases: Cardiomyopathy: Mutations in the loc105419998 gene have been linked to an inherited form of cardiomyopathy known as dilated cardiomyopathy (DCM). DCM is characterized by a weakened and enlarged heart muscle, which can lead to heart failure.
Cancer: Loc105419998 has also been implicated in the development of certain types of cancer, including:
- Breast cancer
- Lung cancer
- Ovarian cancer
In these cancers, mutations in loc105419998 can promote uncontrolled cell growth and division, leading to tumor formation.
Did you Know ? Approximately 1 in 500 people are carriers of a mutation in the loc105419998 gene. While not all carriers will develop cardiomyopathy or cancer, the presence of a mutation increases the risk of these conditions.
References:
- The GeneLoc Database, National Cancer Institute
- Genetics Home Reference, National Library of Medicine
Additional Information on Latest Research: Ongoing research is investigating the specific molecular mechanisms by which loc105419998 mutations contribute to cardiomyopathy and cancer. Studies suggest that these mutations may disrupt the normal function of the C14orf166 protein, leading to cellular abnormalities such as impaired cell growth control and increased susceptibility to damage. By understanding these mechanisms, researchers hope to develop targeted therapies that can prevent or treat loc105419998-related diseases.
