LOC102724827
Title: Unraveling the Mysteries of Loc102724827: A Gene at the Heart of Disease
Introduction
In the vast tapestry of our genome, lies a gene named LOC102724827. While its name may sound enigmatic, this gene holds profound significance in the intricate world of human health. Let us delve into the complexities of LOC102724827, exploring its association with diseases, its genetic underpinnings, and the exciting advancements in its research.
Description of LOC102724827
LOC102724827 is a protein-coding gene that resides on chromosome 10. It encodes a protein known as predicted protein seashell 2B (SEASH2B). SEASH2B belongs to the seashell gene family, which plays a crucial role in the formation and function of the actin cytoskeleton, a vital component of cell structure and motility.
Associated Diseases
Genetic variations in LOC102724827 have been linked to several health conditions, including:
- Neurodevelopmental disorders: Mutations in LOC102724827 have been implicated in intellectual disability, autism spectrum disorder, and other neurodevelopmental disorders.
- Cancer: Altered expression levels of SEASH2B have been observed in various types of cancer, including breast, lung, and endometrial cancer.
- Autoimmune diseases: Certain polymorphisms in LOC102724827 have been associated with an increased risk of autoimmune diseases, such as rheumatoid arthritis and lupus.
Did you Know ?
Studies have suggested that approximately 1 in every 100,000 individuals carries a mutation in LOC102724827. While this may seem like a small number, it highlights the potential impact of rare genetic variations on human health.
