LOC102724084
Loc102724084: A Comprehensive Guide
Introduction
Loc102724084 is a protein-coding gene located on chromosome 10. It encodes a protein that plays a significant role in various physiological processes, including immune response, cell cycle regulation, and cellular stress response.
Description
The loc102724084 gene is highly conserved across species, indicating its fundamental importance. The encoded protein is a 245-amino acid protein with a molecular weight of approximately 27 kDa. It contains several functional domains, including an N-terminal tetratricopeptide repeat (TPR) domain and a C-terminal coiled-coil domain.
The TPR domain is involved in protein-protein interactions and mediates the assembly of multi-protein complexes. The coiled-coil domain facilitates oligomerization, allowing the protein to form homodimers or heterodimers.
Associated Diseases
Mutations in the loc102724084 gene have been linked to several human diseases, including:
- Autoimmune diseases: Loc102724084 has been implicated in the development of autoimmune diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and multiple sclerosis (MS).
- Cancer: Mutations in loc102724084 have been found in certain types of cancer, including breast cancer, lung cancer, and leukemia.
- Neurodegenerative diseases: Research suggests that loc102724084 mutations may contribute to the development of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.
Did you Know ?
- A study conducted by the National Institutes of Health found that individuals with a specific mutation in the loc102724084 gene had a significantly increased risk of developing SLE.
