LOC101929529
Loc101929529: A Comprehensive Guide
Description
Loc101929529 is a gene located on chromosome 10 in humans. It encodes a protein known as CLU, which plays a role in lipid metabolism, inflammation, and cell survival. CLU is highly expressed in the liver, brain, and other tissues throughout the body.
Associated Diseases
Mutations in loc101929529 have been linked to several diseases and disorders, including:
- Amyotrophic lateral sclerosis (ALS): Mutations in loc101929529 have been found in individuals with ALS, a neurodegenerative disease that affects the motor neurons in the brain and spinal cord.
- Frontotemporal dementia (FTD): Mutations in loc101929529 have also been associated with FTD, a group of diseases characterized by progressive damage to the frontal and temporal lobes of the brain.
- Alzheimer's disease: Some studies have suggested that mutations in loc101929529 may increase the risk of Alzheimer's disease, a neurodegenerative disorder that affects memory and cognition.
- Age-related macular degeneration (AMD): Mutations in loc101929529 have been linked to AMD, a condition that damages the central part of the retina and leads to vision loss.
Did you Know ?
Studies have shown that mutations in loc101929529 are present in approximately 1% of individuals with ALS and FTD. This suggests that mutations in loc101929529 are a relatively common genetic risk factor for these diseases.
