LOC101928460
Loc101928460: An Emerging Biomarker in Cancer Detection and Prognosis
Description
Loc101928460 is a long non-coding RNA (lncRNA) molecule that has been identified as a potential biomarker for various types of cancer. LncRNAs are a class of non-coding RNAs that do not encode proteins but play important regulatory roles in gene expression, cellular processes, and disease progression.
Loc101928460 is highly expressed in several cancer types, including lung cancer, breast cancer, and colorectal cancer. Its overexpression has been linked to increased cell proliferation, metastasis, and resistance to therapy. Research suggests that loc101928460 may contribute to cancer development and progression by modulating key cellular signaling pathways involved in cell cycle regulation, DNA repair, and angiogenesis.
Associated Diseases
Loc101928460 has been implicated in the following diseases:
- Lung cancer: Overexpression of loc101928460 in lung cancer is associated with poor prognosis and shorter survival rates.
- Breast cancer: Loc101928460 expression is elevated in breast cancer and correlates with tumor size, lymph node metastasis, and reduced disease-free survival.
- Colorectal cancer: High levels of loc101928460 in colorectal cancer patients have been linked to increased tumor growth, metastasis to the liver, and chemotherapy resistance.
- Other cancers: Loc101928460 has also been associated with esophageal cancer, gastric cancer, and ovarian cancer, suggesting its potential role as a pan-cancer biomarker.
Did you Know ?
A study published in the journal "Nature Medicine" revealed that patients with high loc101928460 expression in their lung cancer tumors had a 60% reduced survival rate compared to those with low expression levels. This striking statistic underscores the potential significance of loc101928460 as a prognostic biomarker in lung cancer.
