LOC101928445
Polycythemia Vera: A Comprehensive Guide
Description
Polycythemia vera (PV) is a chronic blood disorder characterized by an abnormally high red blood cell count, leading to increased blood viscosity and potential complications. It is a type of myeloproliferative neoplasm, where the bone marrow produces excessive amounts of red blood cells, white blood cells, and platelets.
Associated Diseases
PV can be associated with several other conditions, including:
- Thrombosis: Increased blood viscosity can lead to the formation of blood clots in arteries and veins, which can cause strokes, heart attacks, or deep vein thrombosis.
- Cardiovascular disease: Thickened blood can increase the workload on the heart and blood vessels, leading to heart failure or other cardiovascular problems.
- Myelofibrosis: In some cases, PV can progress to myelofibrosis, a condition where the bone marrow is replaced by fibrous tissue, causing anemia and other complications.
- Leukemia: Rarely, PV can transform into acute myeloid leukemia (AML).
Did you Know ?
Approximately 1-2 people per 100,000 are diagnosed with PV each year. The median age at diagnosis is around 60-65 years, and it is more common in men than women.
