LOC101928103
Loc101928103: Delving into a Promising Drug Target for Cancer
Description
Loc101928103 is a protein-coding gene that plays a crucial role in various cellular processes, particularly in DNA repair and maintenance. Located on chromosome 10, it encodes a protein known as WRNIP1 (Werner helicase interacting protein 1). WRNIP1 is involved in the repair of damaged DNA, ensuring the stability and integrity of the genetic material.
Associated Diseases
Mutations in the loc101928103 gene have been linked to several genetic disorders, including:
- Werner syndrome: A progressive genetic disorder characterized by premature aging, including early-onset cataracts, osteoporosis, and cardiovascular disease.
- Bloom syndrome: A rare genetic disorder characterized by increased susceptibility to sunlight, a weakened immune system, and a high risk of developing various types of cancer.
Did you Know ?
Research suggests that individuals with mutations in the loc101928103 gene have a significantly increased risk of developing certain types of cancer, including:
- Breast cancer: A 4-fold increased risk compared to the general population.
- Thyroid cancer: A 7-fold increased risk.
- Lung cancer: A 2-fold increased risk.
- Stomach cancer: A 3-fold increased risk.
