LOC101927100
Understanding Loc101927100 and Its Role in Health
Description
Loc101927100 is a specific gene located on chromosome 16 in humans. It encodes a protein known as long intergenic non-coding RNA 1289 (LINC01289), which plays a vital role in regulating gene expression and cellular processes.
Associated Diseases
Studies have identified associations between loc101927100 and several diseases, including:
- Congenital heart defects: Variations in loc101927100 have been linked to increased risk of certain heart defects in newborns, such as atrial septal defect (ASD).
- Neurodevelopmental disorders: Aberrant expression of LINC01289 has been implicated in neurodevelopmental disorders like autism spectrum disorder (ASD).
- Cancer: Alterations in loc101927100 have been observed in various cancers, including breast cancer, lung cancer, and colorectal cancer.
- Other diseases: Associations have also been found with diseases such as asthma, inflammatory bowel disease, and type 2 diabetes.
Did you Know ?
According to a study published in the journal "Nature Genetics," a specific variant of loc101927100 was found to be associated with an increased risk of congenital heart defects by approximately 20%.
