LOC101926933
Loc101926933: A Comprehensive Guide
Description
Loc101926933 is a gene located on the human chromosome 10. It encodes a protein known as "protein kinase C, eta" (PKCη), which plays crucial roles in various cellular processes, including cell signaling, proliferation, and apoptosis.
Associated Diseases
Dysregulation of loc101926933 and its encoded protein, PKCη, has been linked to several diseases:
- Cardiovascular disease: PKCη has been implicated in the development of cardiac hypertrophy and heart failure.
- Cancer: Abnormal expression of PKCη has been associated with increased cell proliferation and tumor growth in various cancers, including breast, lung, and prostate cancer.
- Neurological disorders: PKCη dysregulation has been linked to Alzheimer's disease, Parkinson's disease, and multiple sclerosis.
- Autoimmune diseases: PKCη may contribute to the inflammatory processes observed in autoimmune diseases such as rheumatoid arthritis and lupus.
Did you Know ?
A study published in the journal "Molecular Cancer" found that overexpression of PKCη was present in 75% of breast cancer cases, suggesting its potential role as a prognostic marker for the disease.
