LOC100133669
Introduction
Loc100133669 is a gene located on chromosome 10. It encodes a protein that is involved in the regulation of cell growth and division. Mutations in this gene have been linked to several types of cancer, including breast cancer, lung cancer, and prostate cancer.
Description
Loc100133669 is a large gene, spanning over 200,000 base pairs. It contains 23 exons and encodes a protein that is 721 amino acids long. The protein is a member of the WD40 repeat family of proteins, which are characterized by their repeating four-amino-acid motif. WD40 proteins are involved in a variety of cellular processes, including cell cycle regulation, signal transduction, and RNA processing.
Associated Diseases
Mutations in loc100133669 have been linked to several types of cancer, including:
- Breast cancer
- Lung cancer
- Prostate cancer
- Colorectal cancer
- Ovarian cancer
- Melanoma
These mutations can lead to the overexpression of the loc100133669 protein, which can in turn promote cell growth and division. This can lead to the development of cancer.
Did you Know ?
A study published in the journal Nature Genetics found that mutations in loc100133669 are present in approximately 10% of breast cancer cases. This suggests that loc100133669 is a significant risk factor for the development of breast cancer.
