LOC100133286
Ulcerative Colitis (UC): A Comprehensive Guide
Description
Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) that affects the large intestine (colon). It causes inflammation and sores (ulcers) in the colon's lining, leading to abdominal pain, diarrhea, and other symptoms.
UC can range in severity from mild to severe, and its course can be unpredictable. It can occur at any age, but it's most commonly diagnosed in people between the ages of 15 and 30.
Associated Diseases
UC is associated with an increased risk of developing:
- Colorectal cancer: People with UC have a higher risk of colon and rectal cancer, especially if they have long-standing disease or extensive involvement of the colon.
- Primary sclerosing cholangitis (PSC): A chronic liver disease that causes inflammation and scarring of the bile ducts.
- Ankylosing spondylitis: A type of inflammatory arthritis that affects the spine and joints.
- Skin disorders: Such as pyoderma gangrenosum and erythema nodosum.
Did you Know ?
- Approximately 1 in 200 people in the United States have UC.
- The incidence of UC is increasing worldwide, with a higher prevalence in developed countries.
