LOC100132215
Polycystic Liver Disease (PLD): A Comprehensive Guide
Description
Polycystic Liver Disease (PLD) is a rare genetic disorder characterized by the development of multiple cysts within the liver. These cysts are fluid-filled sacs that can vary in size and number, ranging from a few millimeters to several centimeters in diameter. PLD is caused by mutations in genes responsible for regulating the formation of bile ducts, the tubes that carry bile from the liver to the intestines.
Associated Diseases
PLD is often associated with other medical conditions, including:
- Polycystic Kidney Disease (PKD): A genetic disorder characterized by the formation of cysts in the kidneys.
- Caroli's Disease: A condition involving the dilation and enlargement of the bile ducts.
- Congenital Hepatic Fibrosis: A rare liver disorder present from birth.
- Nephronophthisis: A rare kidney disease characterized by the progressive loss of nephrons, the functional units of the kidneys.
Did you Know ?
Approximately 1 in 100,000 people worldwide are affected by PLD. It is more common in certain populations, such as the Amish and Mennonite communities.
