LOC100131626
Description
The LOC100131626 (-) is a ncRNA gene located on chromosome 11.
This gene encodes a protein that is a component of the COP9 signalosome (CSN), a multiprotein complex involved in regulating protein degradation by the ubiquitin-proteasome system. The CSN complex is involved in a variety of cellular processes, including signal transduction, cell cycle control, and development. Mutations in this gene have been associated with an increased risk of certain cancers.
The protein encoded by this gene is a member of the tetratricopeptide repeat (TPR) protein family. TPR proteins are characterized by a tandem array of 34-amino-acid repeats that mediate protein-protein interactions. This protein is a component of the COP9 signalosome (CSN), a multiprotein complex that plays a role in regulating protein degradation by the ubiquitin-proteasome system. The CSN complex is involved in a variety of cellular processes, including signal transduction, cell cycle control, and development. Mutations in this gene have been associated with an increased risk of certain cancers.
LOC100131626 is also known as -.