LOC100129550
Lipoprotein(a): An Overlooked Risk Factor for Cardiovascular Disease
Description
Lipoprotein(a) (Lp(a)) is a complex lipoprotein particle that plays a crucial role in blood coagulation and inflammation. It consists of a low-density lipoprotein (LDL) particle attached to a glycoprotein called apolipoprotein(a) (apo(a)). Elevated levels of Lp(a) in the bloodstream are strongly associated with an increased risk of cardiovascular disease, including:
- Coronary artery disease
- Stroke
- Peripheral artery disease
Associated Diseases
Lp(a) has been identified as an independent risk factor for cardiovascular disease, even in individuals with normal levels of LDL cholesterol. Studies have shown that elevated Lp(a) levels are associated with:
- Increased arterial plaque formation
- Thickening of the arterial walls
- Increased inflammation in the blood vessels
- Impaired blood flow to the heart and brain
Did you Know ?
According to the American Heart Association, approximately 20% of the general population has elevated levels of Lp(a). However, the prevalence and impact of Lp(a) may vary across different ethnic and racial groups. For example, African Americans have higher Lp(a) levels on average compared to Caucasians.
