LOC100128176
Description of loc100128176
loc100128176 is a gene located on chromosome 10q21.1. It encodes a protein known as transmembrane protein 100 (TMEM100). TMEM100 is a type II transmembrane protein that is involved in the regulation of cell growth and proliferation. It has been shown to play a role in a number of cellular processes, including cell cycle regulation, apoptosis, and autophagy.
Associated Diseases
Mutations in loc100128176 have been linked to a number of diseases, including:
- Colorectal cancer: Mutations in loc100128176 have been found in approximately 10% of colorectal cancers. These mutations are thought to contribute to the development of cancer by promoting cell growth and proliferation.
- Pancreatic cancer: Mutations in loc100128176 have also been found in approximately 10% of pancreatic cancers. These mutations are thought to contribute to the development of cancer by promoting cell growth and proliferation.
- Gastric cancer: Mutations in loc100128176 have been found in approximately 5% of gastric cancers. These mutations are thought to contribute to the development of cancer by promoting cell growth and proliferation.
- Breast cancer: Mutations in loc100128176 have been found in approximately 5% of breast cancers. These mutations are thought to contribute to the development of cancer by promoting cell growth and proliferation.
Did you Know ?
A study published in the journal Nature Genetics found that mutations in loc100128176 are more common in people of Asian descent than in people of European descent. This suggests that genetic factors may play a role in the development of diseases associated with loc100128176 mutations.
