LOC100126784
Osteoporosis: A Comprehensive Guide
Description
Osteoporosis is a metabolic bone disease characterized by low bone mineral density (BMD) and microarchitectural deterioration of bone tissue, leading to increased bone fragility and susceptibility to fractures. It is a major public health concern, especially among postmenopausal women and older adults.
Osteoporosis occurs when the formation of new bone does not keep pace with the breakdown of old bone. This imbalance leads to a decrease in bone mass and strength, making bones more susceptible to breaks. The condition often progresses silently, without any noticeable symptoms, until a fracture occurs.
Associated Diseases
Several diseases and conditions are associated with an increased risk of developing osteoporosis, including:
- Cushing's syndrome: A condition caused by excessive levels of the hormone cortisol, which can lead to bone loss.
- Hyperthyroidism: An overactive thyroid gland that can cause calcium to be released from bones, reducing BMD.
- Celiac disease: An autoimmune disorder that affects the small intestine and can interfere with calcium absorption.
- Chronic kidney disease: Impaired kidney function can lead to an imbalance of calcium and phosphorus, contributing to bone loss.
- Type 1 diabetes: An autoimmune condition that can cause bone loss, particularly in younger individuals.
Did you Know ?
- According to the International Osteoporosis Foundation, an estimated 200 million people worldwide have osteoporosis. This number is expected to rise to 500 million by 2050.
