LINC01057
linc01057: An Emerging Player in Human Disease
Description
linc01057 is a long non-coding RNA (lncRNA) that plays a crucial role in regulating gene expression and cellular processes. It is located on chromosome 6q24.3 and spans approximately 1.5 kilobases. linc01057 has been found to be involved in various aspects of human health and disease.
Associated Diseases
Deregulation of linc01057 expression has been implicated in the pathogenesis of several diseases, including:
- Cancer: linc01057 has been found to be overexpressed in several types of cancer, including breast, lung, and colon cancer. It promotes cancer cell proliferation, migration, and invasion by regulating various signaling pathways.
- Cardiovascular disease: linc01057 has been linked to the development of atherosclerosis and heart failure. It induces inflammation and oxidative stress, leading to plaque formation and cardiac damage.
- Neurological disorders: linc01057 has been implicated in the pathogenesis of Alzheimer's disease and Parkinson's disease. It contributes to neuronal dysfunction and neuroinflammation, leading to cognitive decline and motor impairments.
Did you Know ?
Research has shown that patients with high expression of linc01057 in their tumor tissues have a significantly worse prognosis compared to those with low expression. This suggests that linc01057 may serve as a potential biomarker for predicting cancer outcomes.
