LINC00969
linc00969: A Potential Biomarker and Therapeutic Target in Cancer
Description
linc00969 is a long non-coding RNA (lncRNA) that plays a crucial role in various cellular processes. It is located on chromosome 11q23.1 and spans approximately 900 nucleotides. linc00969 is highly conserved across different species, suggesting its functional significance.
Associated Diseases
Dysregulation of linc00969 has been implicated in the development and progression of several cancers, including:
- Lung cancer
- Gastric cancer
- Colorectal cancer
- Breast cancer
- Liver cancer
In these cancers, linc00969 often functions as an oncogene, promoting cell proliferation, invasion, and metastasis. It exerts its effects by regulating the expression of target genes involved in cell cycle, apoptosis, and epithelial-mesenchymal transition (EMT).
Did you Know ?
Studies have shown that elevated linc00969 levels are associated with poor prognosis in lung cancer patients. Specifically, patients with high linc00969 expression had significantly shorter overall survival and disease-free survival than those with low expression.
