LINC00893
linc00893: A Long Non-Coding RNA with a Role in Cancer and Other Diseases
Description:
linc00893 is a long non-coding RNA (lncRNA), a type of RNA molecule that does not code for proteins. It is located on chromosome 16q22.1 and is highly conserved across species. linc00893 has been identified as a key regulator of gene expression and is involved in various cellular processes.
Associated Diseases:
Dysregulation of linc00893 has been linked to several diseases, including:
- Cancer: linc00893 is overexpressed in various cancer types, such as breast, gastric, and lung cancer. It promotes tumor growth, metastasis, and resistance to therapy.
- Cardiovascular diseases: linc00893 is associated with coronary artery disease and heart failure. It regulates lipid metabolism and inflammation in the cardiovascular system.
- Neurological disorders: linc00893 is involved in neurodegenerative diseases such as Alzheimer's and Parkinson's disease. It regulates neuronal function and protects against neurotoxicity.
Did you Know ?
According to a study published in the journal "Nature Genetics," over 90% of breast cancer patients with high levels of linc00893 have poor prognosis and reduced survival rates.