LINC00657
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<title>Long Intergenic Non-Protein Coding RNA 657 (linc00657): An Overview</title>
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<h1>Long Intergenic Non-Protein Coding RNA 657 (linc00657)</h1>
<h2>Description</h2>
<p>Long intergenic non-protein coding RNA 657 (linc00657) is a long non-coding RNA (lncRNA) molecule located on the human chromosome 17. LncRNAs are RNA transcripts that do not code for proteins, but they play important roles in various biological processes, including gene regulation, cellular differentiation, and disease development.</p>
<p>Linc00657 has been found to be involved in several biological pathways, including cell proliferation, apoptosis, and metastasis. Studies have shown that lin00657 can act as a tumor suppressor or an oncogene, depending on the cellular context and the type of cancer.</p>
<h2>Associated Diseases</h2>
<p>Linc00657 has been linked to several diseases, including:</p>
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<li>Cancer</li>
<li>Neurological disorders</li>
<li>Cardiovascular diseases</li>
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<p>In cancer, lin00657 has been found to be overexpressed in various types of tumors, including breast cancer, lung cancer, and liver cancer. It has been shown to promote tumor growth, invasion, and metastasis through various mechanisms.</p>
<p>In neurological disorders, linc00657 has been implicated in the development of Alzheimer's disease and Parkinson's disease. It has been found to regulate genes involved in neuronal survival and differentiation.</p>
<p>In cardiovascular diseases, lin00657 has been linked to the development of atherosclerosis and heart failure. It has been found to regulate genes involved in lipid metabolism and vascular inflammation.</p>
**Did you Know ?**
<p>According to a recent study, lin00657 is downregulated in over 50% of breast cancer patients. This suggests that lin00657 may play a protective role against breast cancer development.</p>