LINC00634
linc00634: A Long Non-Coding RNA Implicated in Cancer and Other Diseases
Description
linc00634 is a long non-coding RNA (lncRNA), a type of RNA molecule that does not code for proteins. It is located on chromosome 12 in humans and consists of 1,419 nucleotides. linc00634 is expressed in various tissues, including the lungs, liver, and kidneys. It has been found to play a role in gene regulation, cell cycle control, and apoptosis.
Associated Diseases
Deregulation of linc00634 expression has been linked to several diseases, including:
- Lung cancer: linc00634 is overexpressed in lung cancer tissues and promotes tumor growth and metastasis.
- Colorectal cancer: linc00634 is downregulated in colorectal cancer cells and inhibits tumor cell proliferation.
- Gastric cancer: linc00634 is overexpressed in gastric cancer cells and promotes cell proliferation and invasion.
- Hepatocellular carcinoma: linc00634 is upregulated in hepatocellular carcinoma cells and contributes to tumorigenesis.
Did you Know ?
Studies have shown that linc00634 expression levels are significantly different in cancer patients compared to healthy individuals. For example, in a study of lung cancer patients, linc00634 was found to be overexpressed in 72% of tumor tissues.
