LINC00535
lnc00535: A Long Non-Coding RNA with Emerging Roles in Disease
Description
lnc00535 is a long non-coding RNA (lncRNA) that plays crucial roles in gene regulation and cellular processes. LncRNAs are transcripts that are longer than 200 nucleotides but do not encode proteins. Instead, they interact with DNA, RNA, and proteins to influence gene expression and cellular functions.
lnc00535 is located on chromosome 19q13.4 and has been shown to be involved in various biological processes, including cell proliferation, apoptosis, differentiation, and metabolism. Dysregulation of lnc00535 expression has been linked to several diseases, including cancer and metabolic disorders.
Associated Diseases
Cancer:
- Lnc00535 has been implicated in the development and progression of several types of cancer, including lung cancer, breast cancer, and colon cancer. Overexpression of lnc00535 has been associated with increased tumor cell proliferation, invasion, and metastasis.
Metabolic Disorders:
- Lnc00535 plays a role in regulating glucose and lipid metabolism. Alterations in lnc00535 expression have been associated with type 2 diabetes, obesity, and fatty liver disease.
Other Diseases:
- Lnc00535 has also been linked to other diseases, such as Alzheimer's disease, Parkinson's disease, and cardiovascular disease. However, further research is needed to determine the specific roles of lnc00535 in these diseases.
Did you Know ?
A study published in the journal "Cancer Research" found that overexpression of lnc00535 was associated with a 40% higher risk of lung cancer development. This finding highlights the potential role of lnc00535 as a biomarker for cancer risk assessment.
