LINC00238
linc00238: A Long Non-Coding RNA with Intriguing Roles in Disease
Description
linc00238 is a long non-coding RNA (lncRNA) that plays a crucial role in gene regulation and cellular processes. It is located on chromosome 1q21.3 and has been extensively studied in the context of various diseases.
Associated Diseases
linc00238 has been implicated in the development and progression of several diseases, including:
- Cancer: linc00238 has been found to be overexpressed in several types of cancer, such as breast cancer, lung cancer, and colorectal cancer. It promotes cancer cell proliferation, invasion, and metastasis by regulating key cell signaling pathways.
- Cardiovascular disease: linc00238 has been linked to the development of heart failure and atherosclerosis. It contributes to cardiac remodeling, fibrosis, and inflammation.
- Neurodegenerative diseases: linc00238 has been implicated in the pathogenesis of Alzheimer's disease and Parkinson's disease. It affects neuronal function and promotes neuroinflammation.
Did you Know ?
A study involving over 500 patients with breast cancer found that high levels of linc00238 were associated with a significantly shorter overall survival rate and a higher risk of recurrence.
