LINC00167
linc00167: A Non-Coding RNA with Diverse Roles in Health and Disease
Description:
linc00167 is a long non-coding RNA (lncRNA) located on chromosome 1q23.3. LncRNAs are RNA molecules that do not code for proteins but play crucial roles in gene regulation, cellular processes, and disease development. linc00167 is highly conserved across species, suggesting its functional significance.
Associated Diseases:
linc00167 has been implicated in a range of diseases, including:
- Glioma: Increased linc00167 expression promotes glioma cell growth, migration, and invasion.
- Breast cancer: Low linc00167 expression is associated with poor prognosis and metastasis.
- Lung cancer: linc00167 inhibits cell proliferation and induces apoptosis in lung cancer cells.
- Osteosarcoma: linc00167 suppresses tumor growth and enhances chemosensitivity in osteosarcoma.
Did you Know ?
- A study found that patients with glioma with high linc00167 expression had a significantly shorter overall survival compared to those with low expression.
