LIN52
Description
The LIN52 (lin-52 DREAM MuvB core complex component) is a protein-coding gene located on chromosome 14.
LIN52 is a gene that is involved in regulating the cell cycle and preventing premature entry into mitosis. It is essential for the formation of the spindle pole body, which is a structure that is necessary for chromosome segregation during cell division. The protein encoded by this gene interacts with other proteins, including LIN5 and CSE-4, to ensure that the spindle pole body is formed correctly and that chromosomes are properly separated during cell division.
LIN52 is a gene that plays a role in regulating the cell cycle and preventing premature entry into mitosis. It is involved in the formation of the spindle pole body, a structure that is essential for chromosome segregation during cell division. LIN52 interacts with other proteins, including LIN5 and CSE-4, to ensure proper spindle formation and chromosome stability.
LIN52 is also known as C14orf46, c14_5549.
Associated Diseases
- endometrial cancer
- alpha thalassemia-intellectual disability syndrome type 1
- hemolytic anemia due to adenylate kinase deficiency
- Heinz body anemia
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome
- delta-beta-thalassemia
- hemoglobin D disease
