LIF
Lung Interstitial Fibrosis (LIF): A Comprehensive Guide
Description:
Lung interstitial fibrosis (LIF) is a chronic, progressive disease that affects the delicate tissue (interstitium) between the air sacs of the lungs. This tissue becomes thickened and scarred, impeding the lungs' ability to transfer oxygen to the blood.
Associated Diseases:
LIF can occur as a primary disease or as a secondary complication of various underlying conditions, including:
- Idiopathic pulmonary fibrosis (IPF): The most common type of LIF, with unknown cause.
- Connective tissue diseases: Rheumatoid arthritis, lupus, and scleroderma.
- Pneumoconiosis: Inhalation of certain dusts, such as coal and asbestos.
- Drug reactions: Certain medications, such as methotrexate and amiodarone.
- Radiation therapy: Exposure to high doses of radiation to the chest area.
Did you Know ?
Approximately 50,000 new cases of LIF are diagnosed annually in the United States. The incidence increases significantly with age, with the majority of cases occurring in individuals over 60 years old.