LCN9
Lichen Sclerosis: A Comprehensive Guide to a Chronic Skin Condition
Description
Lichen sclerosis is a chronic skin condition that primarily affects the genital and perianal areas. It causes thin, white patches of skin that can be itchy, painful, and even lead to scarring. While it can occur at any age, lichen sclerosis is most common in postmenopausal women and people over 50.
The exact cause of lichen sclerosis is unknown, but it's believed to be an autoimmune disorder in which the body's immune system mistakenly attacks the skin. Other potential risk factors include:
- Hormonal changes: Lichen sclerosis is often associated with low estrogen levels, which may explain its predominance in postmenopausal women.
- Genetic predisposition: A family history of lichen sclerosis increases the risk of developing the condition.
- Environmental factors: Exposure to certain chemicals or irritants may trigger lichen sclerosis in susceptible individuals.
Associated Diseases
Lichen sclerosis has been linked to several other medical conditions, including:
- Vulvar cancer: Lichen sclerosis is a rare but serious risk factor for vulvar cancer, a type of skin cancer that affects the vulva, the external female genitals.
- Autoimmune disorders: Lichen sclerosis is often associated with other autoimmune disorders, such as thyroid disease, vitiligo, and celiac disease.
- Infections: People with lichen sclerosis may be more susceptible to infections in the genital and perianal areas.
- Psychological distress: The chronic itchiness and discomfort associated with lichen sclerosis can cause significant psychological distress, including anxiety, depression, and sexual dysfunction.
Did you Know ?
- Approximately 1 in 500 women in the United States is affected by lichen sclerosis.
- While lichen sclerosis is often considered a "female" condition, it can also affect men, although less commonly.
