KRTAP5-9


Description

The KRTAP5-9 (keratin associated protein 5-9) is a protein-coding gene located on chromosome 11.

KRTAP5-9 is a hair keratin-associated protein (KRTAP) found in the hair cortex. It forms an interfilamentous matrix that surrounds hair keratin intermediate filaments, playing a crucial role in creating a rigid and resistant hair shaft. This function is achieved through extensive disulfide bond cross-linking with abundant cysteine residues present in hair keratins. KRTAP5-9 belongs to the category of high-sulfur keratins, contributing to the overall structure and strength of hair fibers.

KRTAP5-9 is also known as KRN1, KRTAP5-1, KRTAP5.9.

Associated Diseases



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