KRT75
Description
The KRT75 (keratin 75) is a protein-coding gene located on chromosome 12.
KRT75 is a keratin gene involved in hair shaft structure. While mutations in KRT75 in chickens lead to frizzled feathers, its role in humans remains to be fully understood.
KRT75 plays a vital role in the formation of hair and nails. It's a key component of keratin intermediate filaments in the companion layer of the hair follicle, which contributes to the overall structure and integrity of hair.
KRT75 is also known as CK-75, K6HF, K75, KB18, PFB, hK6hf.
Associated Diseases
- loose anagen syndrome
- Pseudofolliculitis barbae
- esophageal cancer
- low grade glioma
- ringed hair disease
- uncombable hair syndrome
- pili gemini
- pili bifurcati
- wooly hair, autosomal recessive 3
- hypotrichosis simplex
- pili torti
- hypotrichosis 4
- trichodysplasia-xeroderma syndrome
- nonsyndromic congenital nail disorder 3
- autosomal dominant wooly hair
- Marie Unna hereditary hypotrichosis
- monilethrix
- epidermolytic palmoplantar keratoderma
