KRT72
Description of krt72
Keratin 72 (KRT72), also known as the type II hair keratin, is a protein that plays a crucial role in the formation and integrity of hair shafts. It belongs to the keratin family of proteins, which are highly resistant and fibrous. KRT72 is specifically found in the inner layer of the hair shaft, providing strength, elasticity, and protection to the hair.
Associated Diseases
Mutations in the KRT72 gene have been linked to several hair disorders, including:
- Monilethrix: A rare inherited condition characterized by thin, beaded hair shafts that break easily.
- Trichorrhexis invaginata: A condition in which the hair shafts develop small, invaginated areas that cause hair breakage.
- Uncombable hair syndrome: A condition that results in dry, tangled, and unmanageable hair that cannot be combed.
Did you Know ?
Approximately 1 in 100,000 individuals worldwide are affected by monilethrix, a condition associated with KRT72 mutations.
