KRT31
Description
The KRT31 (keratin 31) is a protein-coding gene located on chromosome 17.
KRT31 gene encodes a protein that belongs to the keratin family. This protein is an acidic type I hair keratin and forms hair and nails by heterodimerizing with type II keratins. The type I hair keratins are found in a specific region on chromosome 17q12-q21 and are all transcribed in the same direction.
KRT31 is also known as HA1, Ha-1, KRTHA1, hHa1.
Associated Diseases
- ovarian cancer
- low grade glioma
- isolated congenital hypogonadotropic hypogonadism
- 46,XY complete gonadal dysgenesis
- 46,XX ovotesticular disorder of sex development
- tetragametic chimerism
- nephronophthisis
- multicystic dysplastic kidney
- familial juvenile hyperuricemic nephropathy type 2
