KLHL7-AS1
The KLHL7-AS1 Gene: An Emerging Player in Human Health
Description
The KLHL7-AS1 gene, also known as KLHL7 antisense RNA 1, is a non-coding RNA molecule located on human chromosome 17. It belongs to a class of RNAs called long non-coding RNAs (lncRNAs), which do not code for proteins but play crucial regulatory roles in gene expression.
KLHL7-AS1 is expressed in various tissues and organs, including the brain, heart, liver, and kidneys. It has been implicated in several biological processes, including cell growth, proliferation, and differentiation.
Associated Diseases
Dysregulation of KLHL7-AS1 has been linked to several human diseases, including:
- Cancer: KLHL7-AS1 has been found to be overexpressed in certain types of cancer, such as lung cancer, breast cancer, and liver cancer. It promotes cancer cell growth, invasion, and metastasis.
- Neurological disorders: KLHL7-AS1 has been implicated in the development of neurodegenerative diseases like Alzheimer‘s disease and Parkinson‘s disease. It affects neuronal function and contributes to cognitive impairment.
- Diabetes: KLHL7-AS1 has been associated with type 2 diabetes. It regulates insulin signaling pathways and glucose metabolism.
Did you Know ?
Research suggests that KLHL7-AS1 may be a promising biomarker for early detection of lung cancer. Studies have shown that elevated levels of KLHL7-AS1 in blood samples are associated with an increased risk of developing lung cancer. This finding highlights the potential of KLHL7-AS1 as a non-invasive tool for cancer screening.
